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Theraflu Severe Cold & Congestion Non-Drowsy dan Xadago

Penentuan interaksi Theraflu Severe Cold & Congestion Non-Drowsy dan Xadago dan kemungkinan pengambilan ubat-ubat itu secara bersama-sama.

Hasil pemeriksaan:
Theraflu Severe Cold & Congestion Non-Drowsy <> Xadago
Relevan: 13.03.2023 Pengulas: MD P.M. Shkutko, in

Dalam pangkalan rujukan rasmi yang digunakan untuk membuat perkhidmatan ini, telah didapati interaksi yang dicatat secara statistik berasaskan oleh hasil penyelidikan, yang boleh membawa pada akibat negatif untuk kesihatan pesakit, atau pun meningkatkan kesan positif timbal balik. Dikehendaki rundingan doktor untuk menyelesaikan perkara pengambilan ubat-ubatan secara bersama-sama.

Pengguna:

Menggunakan safinamide bersama-sama dengan dextromethorphan boleh meningkatkan risiko yang jarang tapi serius keadaan yang disebut serotonin sindrom, yang mungkin termasuk gejala-gejala seperti kebingungan, halusinasi, kejang, melampau perubahan dalam tekanan darah, peningkatan detak jantung, demam, berpeluh berlebihan, atau menggigil gemetar, penglihatan kabur, kekejangan otot atau kekakuan, gegaran, ketiadaan koordinasi, perut kejang, mual, muntah, dan diare. Doktor anda mungkin dapat menetapkan alternatif yang tidak berinteraksi, atau anda mungkin perlu lebih kerap pemantauan aman untuk menggunakan kedua-dua ubat-ubatan. Bicaralah dengan doktermu jika kamu memiliki beberapa pertanyaan atau kekhawatiran. Ia adalah penting untuk memberitahu anda dokter tentang semua yang lain ubat-ubatan anda menggunakan, termasuk vitamin dan herba. Jangan berhenti menggunakan mana-mana ubat-ubatan tanpa berbicara dengan anda, doktor.

Profesional:

DISARANKAN: Dengan menghalang serotonin metabolisme, monoamine oxidase (MAOIs), termasuk terpilih MAO-B penindas safinamide, mungkin kekuasaan farmakologis aktiviti serotonin agen seperti dextromethorphan. Hasilnya mungkin peningkatan risiko serotonin sindrom, yang jarang tapi serius dan membawa maut keadaan berpikir untuk hasil dari hyperstimulation dari batang otak 5-HT1A dan 2A reseptor. Gejala serotonin sindrom mungkin termasuk mental perubahan status seperti cepat marah, diubah kesadaran, kekeliruan, halusinasi, dan koma; autisme disfungsi seperti tachycardia, hyperthermia, diaphoresis, menggigil, tekanan darah kelabilan, dan mydriasis; saraf kelainan seperti hyperreflexia, myoclonus, gegaran, ketegaran, dan ataxia; dan pencernaan gejala-gejala seperti kekejangan perut, mual, muntah, dan diare.

PENGURUSAN: Coadministration dari safinamide dengan dextromethorphan dianggap disarankan.

Sumber
  • Diamond S "The use of sumatriptan in patients on monoamine oxidase inhibitors." Neurology 45 (1995): 1039-40
  • Weiner LA, Smythe M, Cisek J "Serotonin syndrome secondary to phenelzine-venlafaxine interaction." Pharmacotherapy 18 (1998): 399-403
  • Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
  • "Product Information. Manerix (moclobemide)." Hoffmann-La Roche Limited, Mississauga, IA.
  • Suchowersky O, deVries JD "Interaction of fluoxetine and selegiline." Can J Psychiatry 35 (1990): 571-2
  • White K, Simpson G "Combined MAOI-tricyclic antidepressant treatment: a reevaluation." J Clin Psychopharmacol 1 (1981): 264-82
  • Fischer P "Serotonin syndrome in the elderly after antidepressive monotherapy." J Clin Psychopharmacol 15 (1995): 440-2
  • Feighner JP, Boyer WF, Tyler DL, Neborsky RJ "Adverse consequences of fluoxetine-MAOI combination therapy." J Clin Psychiatry 51 (1990): 222-5
  • Nierenberg DW, Semprebon M "The central nervous system serotonin syndrome." Clin Pharmacol Ther 53 (1993): 84-8
  • Graham PM, Potter JM, Paterson J "Combination monoamine oxidase inhibitor/tricyclic antidepressants interaction." Lancet 2 (1982): 440
  • Bem JL, Peck R "Dextromethorphan. An overview of safety issues." Drug Saf 7 (1992): 190-9
  • Graber MA, Hoehns TB, Perry PJ "Sertraline-phenelzine drug interaction: a serotonin syndrome reaction." Ann Pharmacother 28 (1994): 732-5
  • Levy AB, Bucher P, Votolato N "Myoclonus, hyperreflexia and diaphoresis in patients on phenelzine- tryptophan combination treatment." Can J Psychiatry 30 (1985): 434-6
  • Phillips SD, Ringo P "Phenelzine and venlafaxine interaction." Am J Psychiatry 152 (1995): 1400-1
  • Martin TG "Serotonin syndrome." Ann Emerg Med 28 (1996): 520-6
  • Sternbach H "Danger of MAOI therapy after fluoxetine withdrawal." Lancet 2 (1988): 850-1
  • Sternbach H "The serotonin syndrome." Am J Psychiatry 148 (1991): 705-13
  • White K, Pistole T, Boyd JL "Combined monoamine oxidase inhibitor-tricyclic antidepressant treatment: a pilot study." Am J Psychiatry 137 (1980): 1422-5
  • Klysner R, Larsen JK, Sorensen P, Hyllested M, Pedersen BD "Toxic interaction of venlafaxine and isocarboxazide." Lancet 346 (1995): 1298-9
  • Gillman PK "Monoamine oxidase inhibitors, opioid analgesics and serotonin toxicity." Br J Anaesth (2005):
  • Bhatara VS, Bandettini FC "Possible interaction between sertraline and tranylcypromine." Clin Pharm 12 (1993): 222-5
  • "Product Information. Cymbalta (duloxetine)." Lilly, Eli and Company, Indianapolis, IN.
  • "Product Information. Fetzima (levomilnacipran)." Forest Pharmaceuticals, St. Louis, MO.
  • Alvine G, Black DW, Tsuang D "Case of delirium secondary to phenelzine/L-tryptophan combination." J Clin Psychiatry 51 (1990): 311
  • Cerner Multum, Inc. "Australian Product Information." O 0
  • Brubacher JR, Hoffman RS, Lurin MJ "Serotonin syndrome from venlafaxine-tranylcypromine interaction." Vet Hum Toxicol 38 (1996): 358-61
  • Bodner RA, Lynch T, Lewis L, Kahn D "Serotonin syndrome." Neurology 45 (1995): 219-23
  • Beasley CM Jr, Masica DN, Heiligenstein JH, Wheadon DE, Zerbe RL "Possible monoamine oxidase inhibitor-serotonin uptake inhibitor interaction: fluoxetine clinical data and preclinical findings." J Clin Psychopharmacol 13 (1993): 312-20
  • Rivers N, Horner B "Possible lethal reaction between nardil and dextromethorphan." Can Med Assoc J 103 (1970): 85
  • "Product Information. Effexor (venlafaxine)." Wyeth-Ayerst Laboratories, Philadelphia, PA.
  • Cetaruk EW, Aaron CK "Hazards of nonprescription medications." Emerg Med Clin North Am 12 (1994): 483-510
  • Chan BSH, Graudins A, Whyte IM, Dawson AH, Braitberg G, Duggin GG "Serotonin syndrome resulting from drug interactions." Med J Aust 169 (1998): 523-5
  • "Product Information. Viibryd (vilazodone)." Trovis Pharmaceuticals LLC, New Haven, CT.
  • De Vita VT, Hahn MA, Oliverio VT "Monoamine oxidase inhibition by a new carcinostatic agent, n-isopropyl-a-(2-methylhydrazino)-p-toluamide (MIH). (30590)." Proc Soc Exp Biol Med 120 (1965): 561-5
  • Schulz R, Antonin KH, Hoffmann E, et al "Tyramine kinetics and pressor sensitivity during monoamine oxidase inhibition by selegiline." Clin Pharmacol Ther 46 (1989): 528-36
  • Mills KC "Serotonin syndrome: A clinical update." Crit Care Clin 13 (1997): 763
  • "Product Information. D.H.E. 45 (dihydroergotamine)." Sandoz Pharmaceuticals Corporation, East Hanover, NJ.
  • Graham PM, Ilett KF "Danger of MAOI therapy after fluoxetine withdrawal." Lancet 2 (1988): 1255-6
  • Pope HG Jr, Jonas JM, Hudson JI, Kafka MP "Toxic reactions to the combination of monoamine oxidase inhibitors and tryptophan." Am J Psychiatry 142 (1985): 491-2
  • Mathew NT, Tietjen GE, Lucker C "Serotonin syndrome complicating migraine pharmacotherapy." Cephalalgia 16 (1996): 323-7
  • Brannan SK, Talley BJ, Bowden CL "Sertraline and isocarboxazid cause a serotonin syndrome." J Clin Psychopharmacol 14 (1994): 144-5
  • Thomas JM, Rubin EH "Case report of a toxic reaction from a combination of tryptophan and phenelzine." Am J Psychiatry 141 (1984): 281-3
  • Corkeron MA "Serotonin syndrome - a potentially fatal complication of antidepressant therapy." Med J Aust 163 (1995): 481-2
  • Jacob JE, Wagner ML, Sage JI "Safety of selegiline with cold medications." Ann Pharmacother 37 (2003): 438-41
  • Spiker DG, Pugh DD "Combining tricyclic and monoamine oxidase inhibitor antidepressants." Arch Gen Psychiatry 33 (1976): 828-30
  • "Product Information. Pristiq (desvenlafaxine)." Wyeth Laboratories, Philadelphia, PA.
  • "Product Information. Savella (milnacipran)." Forest Pharmaceuticals, St. Louis, MO.
  • Sovner R, Wolfe J "Interaction between dextromethorphan and monoamine oxidase inhibitor therapy with isocarboxazid ." N Engl J Med 319 (1988): 1671
  • Heisler MA, Guidry JR, Arnecke B "Serotonin syndrome induced by administration of venlafaxine and phenelzine." Ann Pharmacother 30 (1996): 84
  • Staufenberg EF, Tantam D "Malignant hyperpyrexia syndrome in combined treatment." Br J Psychiatry 154 (1989): 577-8
  • Darcy PF, Griffin JP "Interactions with drugs used in the treatment of depressive illness." Adverse Drug React Toxicol Rev 14 (1995): 211-31
  • Jimenez-Genchi A "Immediate switching from moclobemide to duloxetine may induce serotonin syndrome." J Clin Psychiatry 67 (2006): 1821-1822
  • "Product Information. Xadago (safinamide)." US WorldMeds LLC, Louisville , KY.
  • Diamond S, Pepper BJ, Diamond ML, Freitag FG, Urban GJ, Erdemoglu AK "Serotonin syndrome induced by transitioning from phenelzine to venlafaxine: four patient reports." Neurology 51 (1998): 274-6
  • Gardner DM, Lynd LD "Sumatriptan contraindications and the serotonin syndrome." Ann Pharmacother 32 (1998): 33-8
  • Miller LG "Herbal medicinals: selected clinical considerations focusing on known or potential drug-herb interactions." Arch Intern Med 158 (1998): 2200-11
  • Pettinger WA, Soyangco FG, Oates JA "Inhibition of monoamine oxidase in man by furazolidone." Clin Pharmacol Ther 9 (1968): 442-7
Theraflu Severe Cold & Congestion Non-Drowsy

Nama jenerik: acetaminophen / dextromethorphan / pseudoephedrine

Jenama: Alka-Seltzer Plus Flu Liquigels, Comtrex Non-Drowsy, Dayquil Liquicaps, Daytime Cold, Non-Drowsy Daytime, Robitussin Honey Flu Non-Drowsy, Theraflu Daytime Severe Cold, Theraflu Severe Cold & Congestion Non-Drowsy, Triaminic Cough & Sore Throat, Triaminic Softchew Throat Pain and Cough, Triaminic Softchews Cough & Sore Throat, EQL Severe Cold, GNP Day Time D Cold/Flu, PX Daytime Multi-Symptom, RA Acetaminophen Flu Cold

Sinonim: Theraflu (pseudoephedrine) Daytime Severe Cold

Xadago

Nama jenerik: safinamide

Jenama: Xadago

Sinonim: tidak

Semasa proses kerja digunakan maklumat dari rujukan tersebut: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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