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Actiq dan Zomig (Zolmitriptan Tablets)

Penentuan interaksi Actiq dan Zomig (Zolmitriptan Tablets) dan kemungkinan pengambilan ubat-ubat itu secara bersama-sama.

Hasil pemeriksaan:

Actiq <> Zomig (Zolmitriptan Tablets)

Relevan: 01.10.2022 Pengulas: MD P.M. Shkutko, in

Dalam pangkalan rujukan rasmi yang digunakan untuk membuat perkhidmatan ini, telah didapati interaksi yang dicatat secara statistik berasaskan oleh hasil penyelidikan, yang boleh membawa pada akibat negatif untuk kesihatan pesakit, atau pun meningkatkan kesan positif timbal balik. Dikehendaki rundingan doktor untuk menyelesaikan perkara pengambilan ubat-ubatan secara bersama-sama.

Pengguna:

Menggunakan fentaNYL bersama-sama dengan ZOLMitriptan boleh meningkatkan risiko yang jarang tapi serius keadaan yang disebut serotonin sindrom, yang mungkin termasuk gejala-gejala seperti kebingungan, halusinasi, kejang, melampau perubahan dalam tekanan darah, peningkatan detak jantung, demam, berpeluh berlebihan, atau menggigil gemetar, penglihatan kabur, kekejangan otot atau kekakuan, gegaran, ketiadaan koordinasi, perut kejang, mual, muntah, dan diare. Kes-kes yang teruk boleh menyebabkan keadaan koma dan bahkan kematian. Anda perlu mendapatkan segera medis perhatian jika anda mengalami gejala-gejala ini ketika mengambil ubat-ubatan. Bicaralah dengan doktermu jika kamu memiliki beberapa pertanyaan atau kekhawatiran. Doktor anda mungkin sudah tahu risikonya, tetapi telah ditentukan bahwa ini adalah yang terbaik tentu rawatan untuk anda dan telah mengambil yang sesuai langkah-langkah dan pemantauan anda rapat untuk apa-apa potensi komplikasi. Ia adalah penting untuk memberitahu anda dokter tentang semua yang lain ubat-ubatan anda menggunakan, termasuk vitamin dan herba. Jangan berhenti menggunakan mana-mana ubat-ubatan tanpa berbicara dengan anda, doktor.

Profesional:

MEMANTAU: Seiring menggunakan agen dengan aktiviti serotonin seperti reuptake inhibitor, monoamine oxidase, tricyclic antidepresan, 5-HT1 agonis reseptor, ergot alkaloid, cyclobenzaprine, lithium, St. John, phenylpiperidine opioid, dextromethorphan, dan tryptophan mungkin kekuasaan risiko serotonin sindrom, yang jarang tapi serius dan membawa maut keadaan berpikir untuk hasil dari hyperstimulation dari batang otak 5-HT1A dan 2A reseptor. Gejala serotonin sindrom mungkin termasuk mental perubahan status seperti cepat marah, diubah kesadaran, kekeliruan, halusinasi, dan koma; autisme disfungsi seperti tachycardia, hyperthermia, diaphoresis, menggigil, tekanan darah kelabilan, dan mydriasis; saraf kelainan seperti hyperreflexia, myoclonus, gegaran, ketegaran, dan ataxia; dan pencernaan gejala-gejala seperti kekejangan perut, mual, muntah, dan diare.

PENGURUSAN: Secara umum, seiring menggunakan beberapa serotonin agen harus dielakkan jika mungkin, atau jika tidak mendekati dengan berhati-hati jika potensi manfaat dianggap melebihi risiko. Pesakit perlu dipantau dengan teliti untuk gejala serotonin sindrom semasa rawatan. Berhati-hati khususnya dinasihatkan apabila meningkatkan dos ini agen. Itu risiko yang berpotensi bagi sindrom serotonin harus dianggap bahkan ketika mentadbir serotonin agen secara berurutan, seperti beberapa agen mungkin menunjukkan berpanjangan penghapusan setengah-hidup. Sebagai contoh, ada pakar mencadangkan 5 minggu washout tempoh berikut menggunakan fluoxetine dan 3 minggu berikut menggunakan vortioxetine sebelum mentadbir lain serotonin agen. Individu pelabelan produk untuk washout tempoh yang harus berunding untuk cadangan. Jika serotonin sindrom membangun atau disyaki sepanjang terapi, semua serotonin agen harus dihentikan segera dan mendukung peduli diberikan sebagai perlu. Sederhana pesakit boleh juga mendapat manfaat dari pentadbiran serotonin sesorang (contohnya, cyproheptadine, chlorpromazine). Kes-kes yang teruk harus berjaya di bawah berunding dengan toksikologi dan mungkin memerlukan ubat pelali, saraf lumpuh, intubasi, dan mekanikal pengudaraan di samping langkah-langkah lain.

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